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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL23
All Species:
9.39
Human Site:
S121
Identified Species:
17.22
UniProt:
Q16540
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16540
NP_066957.3
153
17781
S121
K
D
E
S
P
E
G
S
A
A
D
D
L
Y
S
Chimpanzee
Pan troglodytes
XP_508219
185
20823
S153
K
D
E
S
P
E
G
S
A
A
D
D
L
Y
S
Rhesus Macaque
Macaca mulatta
XP_001092196
153
17778
S121
K
D
Q
S
P
E
G
S
T
A
D
G
L
R
D
Dog
Lupus familis
XP_540784
195
22748
P163
K
K
S
P
D
G
S
P
G
D
D
D
I
R
D
Cat
Felis silvestris
Mouse
Mus musculus
O35972
146
17103
D115
P
D
L
F
P
E
K
D
P
R
S
P
E
P
L
Rat
Rattus norvegicus
Q63750
146
17032
E115
P
D
L
F
P
E
K
E
P
T
S
P
D
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517094
106
11828
S75
E
S
S
P
E
P
G
S
F
A
E
I
Q
N
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089781
153
18185
G121
K
D
E
T
P
E
S
G
S
F
D
E
V
Q
M
Zebra Danio
Brachydanio rerio
Q6IQS9
153
18239
G121
K
D
K
K
S
K
E
G
S
V
E
E
M
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W021
150
17859
K119
E
K
A
E
K
Q
A
K
E
E
K
S
L
D
E
Honey Bee
Apis mellifera
XP_001120599
144
17348
E113
D
I
V
P
K
D
S
E
D
K
Y
K
E
Q
V
Nematode Worm
Caenorhab. elegans
Q9GYS9
159
19076
E124
Q
M
F
E
A
L
E
E
D
L
E
L
V
K
A
Sea Urchin
Strong. purpuratus
XP_792235
148
17360
K117
F
P
D
T
E
E
K
K
N
E
E
M
A
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81
92.1
64
N.A.
83.6
84.9
N.A.
30.7
N.A.
65.3
61.4
N.A.
40.5
40.5
32.7
49
Protein Similarity:
100
82.1
96
72.3
N.A.
88.2
89.5
N.A.
47
N.A.
82.3
78.4
N.A.
56.2
60.7
53.4
65.3
P-Site Identity:
100
100
66.6
20
N.A.
20
20
N.A.
20
N.A.
40
13.3
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
100
73.3
26.6
N.A.
20
20
N.A.
33.3
N.A.
66.6
60
N.A.
20
6.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
8
0
16
31
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
54
8
0
8
8
0
8
16
8
39
24
8
16
16
% D
% Glu:
16
0
24
16
16
54
16
24
8
16
31
16
16
0
24
% E
% Phe:
8
0
8
16
0
0
0
0
8
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
31
16
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
47
16
8
8
16
8
24
16
0
8
8
8
0
8
0
% K
% Leu:
0
0
16
0
0
8
0
0
0
8
0
8
31
0
16
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
16
8
0
24
47
8
0
8
16
0
0
16
0
16
0
% P
% Gln:
8
0
8
0
0
8
0
0
0
0
0
0
8
16
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
16
8
% R
% Ser:
0
8
16
24
8
0
24
31
16
0
16
8
0
0
16
% S
% Thr:
0
0
0
16
0
0
0
0
8
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
8
0
0
16
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _